Advances in Molecular and Cellular Endocrinology, Volume 2 by Derek LeRoith

By Derek LeRoith

Quantity 2 has all for points of the pituitary gland either anterior (growth hormone and prolactin receptors, and GH motion) and posterior (vasopressin) pituitary. moreover, thyroid melanoma and steroidogenic enzymes and precocious puberty are lined. ultimately, the "hot issues" contain leptin and progress issue signaling.

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Endocrinol. 10, 45-56. , & Rotwein, P. (1994). Rapid changes in nuclear protein tyrosine phosphorylation after Growth Hormone treatment in v i v o . J. Biol. Chem. 269, 7874-7878. , & Schindler, C. (1996). The SH2 domains of STAT1 and STAT2 mediate multiple interactions in the transduction of INF-t~ signals. EMBO J. 15, 1075-1084. C. (1995). Mapping of the cytoplasmic domain of the human growth hormone receptor required for the activation of JAK2 and STAT proteins. J. Biol. Chem. 270, 21326-21330.

Curr. Opin. Cell. Biol. 7, 176-182. , & Rui, H. (1996). Prolactin activates ras via signaling proteins Shc, growth factor receptor bound 2, and Son of Sevenless. Endocrinology 136, 3512-3518. A. (1996). Convergence of signaling transduced by PRL/cytokine chimeric receptors on PRL-responsive gene transcription. Mol. Endocrinol. 10, 451-460. A. (1995). Cytokine receptor signalling through two novel families of transducer molecules: Janus kinases, and signal transducers and activators of transcription.

Regions of the JAK2 tyrosine kinase required for coupling to the growth hormone receptor. J. Biol. Chem. 270, 14776-14785. A. (1992). Rational design of potent antagonists to the human growth hormone receptor. Science 256, 1677-1679. A. (1993). Mechanism-based design of prolactin receptor antagonists. J. Biol. Chem. 268, 5376-5381. A. (1995). Prolactin receptor antagonists that inhibit the growth of breast cancer cell lines. J. Biol. Chem. 270, 13133-13137. , & Taniguschi, T. (1995). Activation of STAT5 by interleukin 2 requires a carboxy-terminal region of the interleukin 2 receptor 13chain but is not essential for the proliferative signal transmission.

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